Luis A Videla Selected Research

Fatty Liver

1/2022	Influence of the nutritional status and oxidative stress in the desaturation and elongation of n-3 and n-6 polyunsaturated fatty acids: Impact on non-alcoholic fatty liver disease.
2/2020	Impact of the Co-Administration of N-3 Fatty Acids and Olive Oil Components in Preclinical Nonalcoholic Fatty Liver Disease Models: A Mechanistic View.
1/2020	Suppression of high-fat diet-induced obesity-associated liver mitochondrial dysfunction by docosahexaenoic acid and hydroxytyrosol co-administration.
1/2020	Iron-induced derangement in hepatic Δ-5 and Δ-6 desaturation capacity and fatty acid profile leading to steatosis: Impact on extrahepatic tissues and prevention by antioxidant-rich extra virgin olive oil.
11/2019	Docosahexaenoic acid and hydroxytyrosol co-administration fully prevents liver steatosis and related parameters in mice subjected to high-fat diet: A molecular approach.
9/2019	High-fat diet induces mouse liver steatosis with a concomitant decline in energy metabolism: attenuation by eicosapentaenoic acid (EPA) or hydroxytyrosol (HT) supplementation and the additive effects upon EPA and HT co-administration.
10/2018	Molecular mechanisms related to the hepatoprotective effects of antioxidant-rich extra virgin olive oil supplementation in rats subjected to short-term iron administration.
1/2018	Iron-induced pro-oxidant and pro-lipogenic responses in relation to impaired synthesis and accretion of long-chain polyunsaturated fatty acids in rat hepatic and extrahepatic tissues.
1/2018	Attenuation of High-Fat Diet-Induced Rat Liver Oxidative Stress and Steatosis by Combined Hydroxytyrosol- (HT-) Eicosapentaenoic Acid Supplementation Mainly Relies on HT.
12/2017	Supplementation with Docosahexaenoic Acid and Extra Virgin Olive Oil Prevents Liver Steatosis Induced by a High-Fat Diet in Mice through PPAR-α and Nrf2 Upregulation with Concomitant SREBP-1c and NF-kB Downregulation.

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Luis A Videla Research Topics

Disease

26	Non-alcoholic Fatty Liver Disease 03/2022 - 03/2004
26	Fatty Liver 01/2022 - 03/2004
15	Ischemia 09/2018 - 04/2005
14	Inflammation (Inflammations) 04/2022 - 11/2011
13	Insulin Resistance 03/2022 - 10/2009
12	Obesity 10/2020 - 11/2004
7	Mitochondrial Diseases (Mitochondrial Disease) 03/2022 - 01/2018
5	Acute-Phase Reaction 03/2022 - 05/2006
4	Necrosis 03/2022 - 03/2002
4	Reperfusion Injury 03/2022 - 08/2010
4	Iron Overload 03/2022 - 08/2005
4	Hyperthyroidism 03/2006 - 07/2002
3	Liver Diseases (Liver Disease) 09/2021 - 11/2011
3	Brain Death (Brain Dead) 08/2016 - 05/2015
3	Body Weight (Weight, Body) 06/2014 - 03/2002
2	Hypertrophy 09/2020 - 01/2019
2	Fibrosis (Cirrhosis) 02/2020 - 11/2011
1	Fever (Fevers) 04/2022
1	Respiratory Tract Diseases (Respiratory Tract Disease) 04/2022
1	Chronic Obstructive Pulmonary Disease (COPD) 04/2022
1	Asthma (Bronchial Asthma) 04/2022
1	Cardiovascular Diseases (Cardiovascular Disease) 01/2018

Drug/Important Bio-Agent (IBA)

19	Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA 04/2022 - 06/2004
14	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 03/2022 - 01/2011
13	AntioxidantsIBA 03/2022 - 03/2004
10	Docosahexaenoic AcidsIBA 04/2022 - 01/2008
10	Fatty Acids (Saturated Fatty Acids)IBA 03/2022 - 11/2004
9	Thyroid HormonesIBA 03/2022 - 05/2006
9	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2022 - 10/2002
9	Sterol Regulatory Element Binding Protein 1IBA 10/2020 - 11/2009
9	Proteins (Proteins, Gene)FDA Link 10/2018 - 03/2004
7	LipidsIBA 04/2022 - 06/2004
7	EnzymesIBA 01/2022 - 03/2006
7	Messenger RNA (mRNA)IBA 01/2020 - 08/2003
7	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 09/2018 - 07/2002
6	IronIBA 03/2022 - 08/2011
6	3,4-dihydroxyphenylethanol (hydroxytyrosol)IBA 01/2022 - 01/2018
6	Glutathione (Reduced Glutathione)IBA 10/2021 - 10/2002
6	NF-kappa B (NF-kB)IBA 12/2017 - 08/2003
5	Eicosapentaenoic AcidIBA 04/2022 - 01/2011
5	Transcription Factors (Transcription Factor)IBA 03/2022 - 03/2006
5	Omega-3 Fatty Acids (Omega 3 Fatty Acids)IBA 01/2022 - 01/2008
5	Phospholipids (Phosphatides)FDA LinkGeneric 10/2020 - 06/2004
5	Triglycerides (Triacylglycerol)IBA 02/2020 - 06/2004
5	DNA (Deoxyribonucleic Acid)IBA 06/2014 - 08/2003
4	SterolsIBA 03/2022 - 05/2011
4	Triiodothyronine (Liothyronine)FDA LinkGeneric 03/2022 - 10/2002
4	ElementsIBA 03/2022 - 05/2011
4	CytokinesIBA 05/2021 - 08/2003
4	AcidsIBA 01/2020 - 07/2010
3	Adenosine Triphosphate (ATP)IBA 01/2022 - 09/2019
3	Carnitine (L-Carnitine)FDA LinkGeneric 10/2018 - 11/2009
3	Interleukin-6 (Interleukin 6)IBA 01/2016 - 05/2006
3	InterleukinsIBA 01/2012 - 08/2003
3	Cytochrome P-450 CYP2E1 (CYP2E1)IBA 01/2008 - 03/2004
2	AMP-Activated Protein KinasesIBA 03/2022 - 01/2017
2	ImmunosorbentsIBA 10/2020 - 09/2020
2	Olive OilIBA 02/2020 - 12/2017
2	fibroblast growth factor 21IBA 01/2020 - 11/2016
2	InflammasomesIBA 01/2019 - 01/2017
2	Oleic Acid (Oleate)IBA 10/2018 - 01/2018
2	Acyl-CoA OxidaseIBA 10/2018 - 06/2014
2	Transaminases (Aminotransferases)IBA 09/2018 - 01/2018
2	Insulin (Novolin)FDA Link 01/2016 - 01/2016
2	PPAR alphaIBA 06/2014 - 11/2009
2	Acetylcysteine (Siran)FDA LinkGeneric 01/2013 - 01/2009
2	Fish OilsIBA 09/2012 - 08/2010
2	Transcription Factor AP-1 (Transcription Factor AP 1)IBA 01/2012 - 05/2009
2	AdiponectinIBA 05/2011 - 11/2009
2	F2-Isoprostanes (F2 Isoprostanes)IBA 01/2008 - 01/2007
2	Chlorzoxazone FDA LinkGeneric 01/2008 - 01/2006
2	CatalaseIBA 03/2004 - 10/2002
1	HepcidinsIBA 03/2022
1	Ferritins (Ferritin)IBA 03/2022
1	Free RadicalsIBA 01/2022
1	Pharmaceutical PreparationsIBA 01/2022
1	ChemokinesIBA 05/2021
1	Peptide Hydrolases (Proteases)FDA Link 05/2021
1	PPAR gammaIBA 09/2020
1	NAD (NADH)IBA 01/2020
1	GA-Binding Protein Transcription FactorIBA 09/2019
1	Leucine (L-Leucine)FDA Link 01/2019
1	PyrinIBA 01/2019
1	NucleotidesIBA 01/2019
1	Acetyl-CoA CarboxylaseIBA 10/2018
1	Tocopherols (Tocopherol)IBA 10/2018
1	TransferasesIBA 10/2018
1	Citrate (si)-Synthase (Synthase, Citrate)IBA 10/2018
1	NADP (NADPH)IBA 09/2018
1	thiobarbituric acidIBA 09/2018
1	Heme Oxygenase-1IBA 09/2018
1	quinone (benzoquinone)IBA 09/2018
1	oleuropeinIBA 01/2018
1	Monounsaturated Fatty AcidsIBA 01/2018

Therapy/Procedure

6	Gastrectomy 05/2011 - 03/2006
5	Therapeutics 02/2020 - 01/2016
3	Liver Transplantation 02/2020 - 04/2005
3	Laparoscopic Cholecystectomy 05/2011 - 11/2009
2	Drug Therapy (Chemotherapy) 12/2017 - 10/2015
2	Transplantation 05/2015 - 09/2012